Stem Cell Research & Regenerative Medicine
Regenerative medicine is a discipline that studies the repair and regeneration of damaged tissues and organs. For modern medicine, this amazing medical technology is absolutely revolutionary.
Regenerative medicine represents the entry of medicine into new era of reconstruction, regeneration, "manufacturing", and replacement of tissues and organs, bringing new hope to most medical problems faced by human beings.
In theory, all tissue and organ damage caused by diseases can be cured by regenerative medicine technology. With the development and deepening of research, the connotation of regenerative medicine has been continuously expanded, including tissue engineering, cell and cytokine therapy, gene therapy and microecological therapy.
The widespread application of regenerative medicine largely depends on the progress of stem cell research. Stem cells are the basis of tissue regeneration. To achieve the regeneration of damaged organs and tissues, stem cells are one of the most important ways, and the basis of tissue regeneration is the result of the orderly differentiation and regulation of various repair cells (including stem cells).
Stem cell research is the frontier and hotspot of today's biomedical research. It is developing rapidly in the world and has become one of the most transformative research fields, and promotes the common progress of other related fields. A new round of stem cell biology research in the 1990s laid a scientific foundation for the development of regenerative medicine, and the establishment of tissue engineering provided basic technical means and methods for the clinical application of regenerative medicine.
AGH Regenerative Medicine Center
AGH Regenerative Medicine Center aims to replace, repair, reconstruct or regenerate various tissues and organs of the human body with "regenerative medicine" as the main line, focusing on stem cell technology, molecular gene regulation technology, somatic cell reprogramming technology, tissue engineering technology, etc.
It has a high-level research, production and application base of a certain scale, forming an effective technology development and application system. The center's primary mission is to focus on stem cell research, optimizing the expansion, differentiation, and transplantation of stem cells, as well as the isolation, extraction and preparation of cytokines and exosomes.
The aim is to build an international platform linking basic research and clinical applications of regenerative medicine.
At present, the center has reserved a series of stem cell products and industrialization results and is committed to further screening and optimizing stem cells and their derived products with market prospects and clinical application value.
Primary Technology Products
1. Stem Cell Three-Dimensional Mini-Skin Patented Technology
AGH's patented stem cell three-dimensional mini-skin technology is a mini-skin structure that integrates epidermal cells and dermal cells in vitro. The mini-skin structure is simple to prepare and easy to promote, and can be used to implant in vivo or active in vitro cultured organs to provide healthy cells as a cell bank.
The mini-skin structure can also be used to test the safety and efficacy of drugs or cosmetics; additionally, it can be used to develop in vitro disease models and as a three-dimensional cellular model to study the interaction of dermal and epidermal cells under pathological and physiological environmental conditions.
Stem cell three-dimensional mini-skin patented technology adopts particle suspension technology, surface tension transfer technology, epidermal stem cell extraction technology and biological cell selection technology. It is the only in vitro synthetic and transplantable active organ containing stem cell germinal layer in the field of international regenerative medicine.
This technology subversively changes the clinical repair mode of wound healing, replacing the passive repair mode of traditional wound products with the active repair mode of stem cells, promoting wound healing and improving the quality of repair.
Key Advantages:
- • Eliminates the need for collagen grids and additional biomaterials
- • Only skin replacement product containing active stem cells
- • Continuous supply of active new cells
- • Simple production with short duration and low costs
- • Can be mass produced with long lifecycle
- • Can be frozen and stored for easy transportation
- • Allogeneic application is possible
Future Applications:
Clinical Applications:
- • Spray preparations for trauma treatment
- • Biological dressing products
- • Mini-active artificial skin
- • Ointments, aerosols, and dressings
Research & Development:
- • Disease models (scar, muscle damage, cardiovascular)
- • Hair follicle models
- • Biological kit products
- • Adult stem cell extraction kits
2. UCF Full Array Cytokine Patented Technology
Cytokines are small molecule polypeptides or glycoproteins synthesized and secreted by a variety of tissue cells, with a variety of biological functions, such as regulating cell growth, differentiation and maturation, function maintenance, regulating immune responses, participating in inflammatory responses, wound healing and tumor growth.
Stem cell factors refer to important factors that can target and regulate the stemness maintenance, directional differentiation and other characteristics of stem cells, as well as active factors that are produced in stem cell therapy and play a key role in repairing damage. Through the application of stem cell factors, targeted intervention is carried out on the intrinsic stem cells of damaged tissues to restore and activate the function of intrinsic stem cells, promote tissue repair and regeneration, and achieve cell-free stem cell therapy.
Umbilical Cord Blood
Umbilical cord blood refers to the blood that remains in the placenta and umbilical cord after the fetus is delivered and the umbilical cord is ligated and severed. Umbilical cord blood contains a large number of stem cells and cytokines, including hematopoietic stem cells and a variety of other stem cells and factors.
Cord blood contains more than 700 cytokines, chemokines, etc. in six categories, which coordinate cell growth, proliferation, differentiation and maturation. Fresh umbilical cord blood stem cell factor (UCF) purified by a special method can directly activate human stem cells, achieve cell repair and improvement of body functions, rejuvenate the body, and complete real functional reversal.
AGH's UCF Technology
AGH Holding's Umbilical Cord Blood Cytokine (UCF) is an allogeneic, sterile, lyophilized, full-array cytokine product derived from human cord blood plasma, containing a range of (full-array) cytokines, chemokines, and important exosomes which have biological effects on immune responses, and which has shown consistent distribution and characteristics in different batches.
These full-array UCF cord blood cytokine combinations showed a completely different, unique and stronger anti-inflammatory and regenerative capacity than blood cytokines from more mature age groups (18-65 years old). The unique advantage of UCF is that it is not a single cytokine, but rather a collection of more than 700 full arrays of cytokines in six categories.
Revolutionary Breakthrough
UCF's patented technology completely breaks through the level of stem cells and enters the field of smaller but more powerful cytokines; it is directly extracted from the umbilical cord blood of the youngest "zero"-year-old baby. The refined and selected full array of cord blood cytokines has been found and confirmed to have the best combination array, the most powerful repairing power and the most lasting and thorough effect.
It breaks through the time limit of cell product activity, maintains long-term activity, and enters standardized commodities era.
Umbilical cord blood cytokine (UCF) is a full array of cord blood cell total factors that are selected, isolated, purified and optimized according to special standards. This is the most unique cell regenerative medicine repair grade product in the world. Experiments have proved that it is an absolutely safe and effective product, and has a production license issued by the Australian Drug Administration and a legal sales and export license issued by the Australian government.